Prize sponsor: proSET (Professionals in SET), a sector of the NSTF representing almost 50 professional societies
- Prof Sally Archibald – Professor: School of Plant and Animal Sciences, University of the Witwatersrand (Wits)
- Prof Irene Barnes – Professor of Genetics: Department (Dept) of Biochemistry, Genetics and Microbiology; Research Leader: Forestry and Agricultural Biotechnology Institute; University of Pretoria (UP)
- Prof Stephen Brown – Senior (Sr) Lecturer and Head: Paediatric Cardiology, Universitas Academic Hospital, Free State Department of Health and University of the Free State (UFS); and also in the Clinician-Scientist category*
- Prof Francois J Cleophas – Associate Professor, Division of Sport Science, Stellenbosch University (SU)
- Dr Tatenda Dalu – Sr Lecturer: School of Biology and Environmental Sciences, University of Mpumalanga (UMP); Honorary Research Associate: South African Institute (Inst) for Aquatic Biodiversity
- Prof Charlenè Downing – Professor: Dept of Nursing, Faculty of Health Sciences, University of Johannesburg (UJ)
- Prof Admire Dube – Professor, School of Pharmacy; Deputy Dean: Learning and Teaching, University of the Western Cape (UWC)
- Prof Timothy Dube – Director: Inst for Water Studies, UWC; Adjunct Professor: United Nations University, Flores, Germany; and also in the Water Research Commission category*
- Prof Blassan George – Professor: Laser Research Centre, Faculty of Health Sciences, UJ
- Dr Omowunmi Isafiade – Sr Lecturer: Dept of Computer Science, Faculty of Natural Science, UWC
- Dr Mankgopo Kgatle – Extraordinary Lecturer and Head: Basic and Translational Research (Nuclear Medicine Research Infrastructure), UP
- Dr Elizaveta Kovaleva – Lecturer: Applied Geology Section, Dept of Earth Science, UWC
- Prof Alex T Kuvarega – Thematic Area Leader: Nanostructured Materials, Inst for Nanotechnology and Water Sustainability, College of Science, Engineering and Technology, University of South Africa (UNISA)
- Dr Michelle Lochner – Sr Lecturer: Dept of Physics and Astronomy, UWC; Staff Scientist: SA Radio Astronomy; and also in the Special Annual Theme category*
- Dr Gerald Maarman – Sr lecturer: Division of Medical Physiology, Dept of Biomedical Sciences, Faculty of Medicine and Health Sciences, SU
- Prof Thulani Makhalanyane – Professor: Dept of Microbiology; Professor: School for Data Science and Computational Thinking, SU
- Prof Nomusa Makhubu – Associate Professor: Art History, University of Cape Town (UCT)
- Prof Cletos Mapiye – Associate Professor: Animal Science, SU
- Prof Pontsho Mbule – Associate Professor, Dept of Physics, UNISA
- Dr Teboho C Mokhena – Head: Nanomaterials Unit; Principal Research Scientist: Advanced Materials Division, Mintek; and also in the Management category*
- Prof Deshen Moodley – DSI/NRF-UCT SARChI Chair in Artificial Intelligence (AI) Systems; Co- Director: Centre for Artificial Intelligence Research, Dept of Computer Science, UCT; and also in the Special Annual Theme category*
- Prof Khumbulani Mpofu – Chair: DSI/NRF South African Research Chairs Initiative (SARChI) in Future Transport Manufacturing Technologies; Gibela Research Chair in Manufacturing and Skills Development; Founder and Board Member: Rail Manufacturing Centre for Entrepeneurship Rapid Incubator, Tshwane University of Technology (TUT); also in the Engineering Research Capacity Development and the Special Annual Theme categories*
- Prof Patience Mthunzi-Kufa – Research Group Head for Biophotonics and Manager (Photonics Centre) – Council for Scientific and Industrial Research (CSIR); Professor Extraordinarius: UNISA; and also in the Management and the Engineering Research Capacity Development categories*
- Prof Ricky M Mukonza – Associate Professor: Academic Manager, TUT
- Dr Suresh Babu Naidu Krishna – Research Fellow: Dept of Biomedical and Clinical Technology: Durban University of Technology (DUT)
- Prof Gordon O’Brien – Associate Professor: Ecology and Programme Leader: “Rivers of Life”, UMP; and also in the Water Research Commission category
- Prof Samuel O Oluwafemi – Professor and Project Leader: Nanomaterials Synthesis and Applications Laboratory, Dept of Chemical Sciences, UJ; and also in the Engineering Research Capacity Development category*
- Dr Ramesh Pandian – Researcher: Protein Structure-Function Research Unit, School of Molecular and Cell Biology, Wits
- Prof Umesh Ramnarain – Professor: Science Education; Director: Centre for Advanced Learning Technologies in Science, Technology, Engineering, Arts and Mathematics, Faculty of Education, UJ; and also in the Communications category*
- Prof Mahloro H Serepa-Dlamini – Associate Professor and Head of Department: Biotechnology and Food Technology, UJ
- Prof Sudesh Sivarasu – Chair: DSI/NRF SARChI in Biomedical Engineering and Innovation; Director: Biomedical Engineering Research Centre; Head: UCT MedTech, UCT; and also in the Engineering Research Capacity Development and in the Innovation: Corporate Organisation categories*
- Prof Grant Theron – P Group Leader: DSI/NRF CoE for Biomedical TB Research, South African Medical Research Council Centre for TB Research, Dept of Biomedical Sciences, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, SU
- Dr Fidele Tugizimana – Lecturer and Research Scientist, Deputy HoD: Dept of Biochemistry, UJ; co-Director of the Research Centre for Plant Metabolomics, UJ; Specialist Scientist: International Research and Development Division, Omnia Nutriology, Omnia Group Ltd, SA
- Dr Zikhona Tywabi-Ngeva – Lecturer and Researcher: Dept of Chemistry, Nelson Mandela University, Gqeberha; and also in the Emerging Researcher and in the Green Economy categories*
- Dr Bjorn von der Heyden – Sr Lecturer: Dept of Earth Sciences, African Rainbow Minerals GeoMetallurgy Research Co-Chair, SU